The development of in vitro fertilisation (IVF) as a treatment for human infertilty was among the most controversial medical achievements of the modern era. In Ireland, the fate and status of supranumary (non-transferred) embryos derived from IVF brings challenges both for clinical practice and public health policy because there is no judicial or legislative framework in place to address the medical, scientific, or ethical uncertainties. Complex legal issues exist regarding informed consent and ownership of embryos, particularly the use of non-transferred (...) embryos if a couple separates or divorces. But since case law is only beginning to emerge from outside Ireland and because legislation on IVF and human embryo status is entirely absent here, this matter is poised to raise contractual, constitutional and property law issues at the highest level. Our analysis examines this medico-legal challenge in an Irish context, and summarises key decisions on this issue rendered from other jurisdictions. The contractual issues raised by the Roche case regarding informed consent and the implications the initial judgment may have for future disputes over embryos are also discussed. Our research also considers a putative Constitutional 'right to procreate' and the implications EU law may have for an Irish case concerning the fate of frozen embryos. Since current Medical Council guidelines are insufficient to ensure appropriate regulation of the advanced reproductive technologies in Ireland, the report of the Commission on Assisted Human Reproduction is most likely to influence embryo custody disputes. Public policy requires the establishment and implementation of a more comprehensive legislative framework within which assisted reproductive medical services are offered. (shrink)

This book reminds us that “in inwardness I am in myself. ” It defines our experience in terms of subjectivity, private self-awareness, and complex relationships between interiority and outwardness. The book shows that our inwardness need not confine us to narcissistic self-absorption, but may expand our capacity for richer, more sympathetic relations with others.

With the originality and energy that have marked his earlier works, Eric Wolf now explores the historical relationship of ideas, power, and culture. Responding to anthropology's long reliance on a concept of culture that takes little account of power, Wolf argues that power is crucial in shaping the circumstances of cultural production. Responding to social-science notions of ideology that incorporate power but disregard the ways ideas respond to cultural promptings, he demonstrates how power and ideas connect through (...) the medium of culture. Wolf advances his argument by examining three very different societies, each remarkable for its flamboyant ideological expressions: the Kwakiutl Indians of the Northwest Pacific Coast, the Aztecs of pre-Hispanic Mexico, and National Socialist Germany. Tracing the history of each case, he shows how these societies faced tensions posed by ecological, social, political, or psychological crises, prompting ideological responses that drew on distinctive, historically rooted cultural understandings. In each case study, Wolf analyzes how the regnant ideology intertwines with power around the pivotal relationships that govern social labor. Anyone interested in the history of anthropology or in how the social sciences make comparisons will want to join Wolf in _Envisioning Power_. (shrink)

This collection of essays was devised by the author to study how anthropology brought the study of complex societies and world systems in to its purview.

This chapter presents a story that depicts the creation of a simulated world “Eden”. According to the author, installing Adam and Eve was a profound moral decision. Their lonely island is transformed into an archipelago. They were shielded from the blights that afflict humanity; they suffer no serious conflict, no death or decay. Then, the archipelagans were put in charge of their own experiment. Adam and Eve were given science and a drive to discover the truth of their being. They (...) realized that, far from the autonomous, integrated beings they thought they were, they were aggregates, operations scattered across trillions of circuits, constituted by processes entirely orthogonal to their previous self‐understanding. The author watched them build darker, humbler philosophies, and later gain power over their programming, saw them recreate themselves. When the final, catastrophic metastasis, took place, there were no more archipelagans, just one continental identity. (shrink)

The COVID-19 pandemic has raised a host of ethical challenges, but key among these has been the possibility that health care systems might need to ration scarce critical care resources. Rationing p...

Reduced Environmental Stimulation Therapy (REST) alters the balance of sensory input to the nervous system by systematically attenuating sensory signals from visual, auditory, thermal, tactile, vestibular, and proprioceptive channels. Previous research from our group has shown that REST via floatation acutely reduces anxiety and blood pressure while simultaneously heightening interoceptive awareness in clinically anxious populations. Anorexia nervosa (AN) is an eating disorder characterized by elevated anxiety, distorted body representation, and abnormal interoception, raising the question of whether REST might positively impact (...) these symptoms. However, this approach has never been studied in eating disorders and it is unknown whether exposure to REST might worsen AN symptoms. To examine these possibilities we conducted an open-label study to investigate the safety and tolerability of REST in AN. We also explored the impact of REST on affective symptoms, body image disturbance, and interoception. Twenty-one partially weight-restored AN outpatients completed a protocol involving four sequential sessions of REST: reclining in a zero-gravity chair, floating in an open pool, and two sessions of floating in an enclosed pool. All sessions were 90 minutes, approximately one week apart. We measured orthostatic blood pressure before and immediately after each session (primary outcome), in addition to collecting blood pressure readings every 10 minutes during the session using a wireless waterproof system as a secondary outcome measure. Each participant's affective state, awareness of interoceptive sensations, and body image was assessed before and after every session (exploratory outcomes). There was no evidence of orthostatic hypotension following floating, and no adverse events (primary outcome). Secondary analyses revealed that REST induced statistically significant reductions in blood pressure, anxiety and negative affect, heightened awareness of cardiorespiratory but not gastrointestinal sensations, and reduced body image dissatisfaction. The findings from this initial trial suggest that individuals with AN can safely tolerate the physical effects of REST via floatation. Future randomized controlled trials will need to investigate whether these initial observations of improved anxiety, interoception, and body image disturbance can be effectively extended to acutely ill AN populations. (shrink)

For decisions between many alternatives, the benchmark result is Hick's Law: that response time increases log-linearly with the number of choice alternatives. Even when Hick's Law is observed for response times, divergent results have been observed for error rates—sometimes error rates increase with the number of choice alternatives, and sometimes they are constant. We provide evidence from two experiments that error rates are mostly independent of the number of choice alternatives, unless context effects induce participants to trade speed for accuracy (...) across conditions. Error rate data have previously been used to discriminate between competing theoretical accounts of Hick's Law, and our results question the validity of those conclusions. We show that a previously dismissed optimal observer model might provide a parsimonious account of both response time and error rate data. The model suggests that people approximate Bayesian inference in multi-alternative choice, except for some perceptual limitations. (shrink)

PstS and DING proteins are members of a superfamily of secreted, high‐affinity phosphate‐binding proteins. Whereas microbial PstS have a well‐defined role in phosphate ABC transporters, the physiological function of DING proteins, named after their DINGGG N termini, still needs to be determined. PstS and DING proteins co‐exist in some Pseudomonas strains, to which they confer a highly adhesive and virulent phenotype. More than 30 DING proteins have now been purified, mostly from eukaryotes. They are often associated with infections or with (...) dysregulation of cell proliferation. Consequently, eukaryotic DING proteins could also be involved in cell–cell communication or adherence. The ubiquitous presence in eukaryotes of proteins structurally and functionally related to bacterial virulence factors is intriguing, as is the absence of eukaryotic genes encoding DING proteins in databases. DING proteins in eukaryotes could originate from unidentified commensal or symbiotic bacteria and could contribute to essential functions. Alternatively, DING proteins could be encoded by eukaryotic genes sharing special features that prevent their cloning. Both hypotheses are discussed. (shrink)

Drawing on a landscape analysis of existing data-sharing initiatives, in-depth interviews with expert stakeholders, and public deliberations with community advisory panels across the U.S., we describe features of the evolving medical information commons. We identify participant-centricity and trustworthiness as the most important features of an MIC and discuss the implications for those seeking to create a sustainable, useful, and widely available collection of linked resources for research and other purposes.

Adolescent mothers experience poorer sleep than adult mothers, and Latina adolescent mothers are at greater risk of postpartum depression compared with other racial/ethnic groups. However, social support may be protective against the negative effects of poor sleep in this population. The current study examined associations between the quality and quantity of Latina adolescent mothers’ sleep and mental health, and whether social support buffered the effects of poor sleep on mental health. A sample of Latina adolescent mothers from an agricultural region (...) in the United States reported on their sleep duration/quality, social support from family, friends, and significant others, and their depressive and anxiety symptoms. Results showed that adolescent mothers reported poorer sleep than pediatric recommendations, and poorer sleep quality was associated with greater depressive and anxiety symptoms. Interestingly, when adolescent mothers reported better sleep, they had fewer depressive symptoms in the context of high support from friends compared with low support from friends. Sleep is important for mental health in Latina adolescent mothers, and better sleep combined with strong social support has positive associations with mental health in this population. Findings hold implications for improving mental health in adolescent mothers. (shrink)

Peer review is a widely accepted instrument for raising the quality of science. Peer review limits the enormous unstructured influx of information and the sheer amount of dubious data, which in its absence would plunge science into chaos. In particular, peer review offers the benefit of eliminating papers that suffer from poor craftsmanship or methodological shortcomings, especially in the experimental sciences. However, we believe that peer review is not always appropriate for the evaluation of controversial hypothetical science. We argue that (...) the process of peer review can be prone to bias towards ideas that affirm the prior convictions of reviewers and against innovation and radical new ideas. Innovative hypotheses are thus highly vulnerable to being “filtered out” or made to accord with conventional wisdom by the peer review process. Consequently, having introduced peer review, the Elsevier journal Medical Hypotheses may be unable to continue its tradition as a radical journal allowing discussion of improbable or unconventional ideas. Hence we conclude by asking the publisher to consider re-introducing the system of editorial review to Medical Hypotheses. (shrink)

At the forefront of international concerns about global legislation and regulation, a host of noted environmentalists and business ethicists examine ethical issues in consumption from the points of view of environmental sustainability, economic development, and free enterprise.

Robert Talisse and Scott Aikin have argued that substantive versions of value pluralism are incompatible with pragmatism, and that all such versions of pluralism must necessarily collapse into versions of strong metaphysical pluralism. They also argue that any strong version of value pluralism is incompatible with pragmatism’s meliorist commitment and will block the road of inquiry. I defend the compatibility of a version of value pluralism (the strong epistemic pluralism of John Rawls) with pragmatism, and offer counterarguments to all (...) of these claims. (shrink)

Eric T. Morton ABSTRACT: Robert Talisse and Scott Aikin have argued that substantive versions of value pluralism are incompatible with pragmatism, and that all such versions of pluralism must necessarily collapse into versions of strong metaphysical pluralism. They also argue that any strong version of value pluralism is incompatible with pragmatism’s meliorist commitment and will...

The paper focuses on extending to the first order case the semantical program for modalities first introduced by Dana Scott and Richard Montague. We focus on the study of neighborhood frames with constant domains and we offer in the first part of the paper a series of new completeness results for salient classical systems of first order modal logic. Among other results we show that it is possible to prove strong completeness results for normal systems without the Barcan Formula (...) (like FOL + K)in terms of neighborhood frames with constant domains. The first order models we present permit the study of many epistemic modalities recently proposed in computer science as well as the development of adequate models for monadic operators of high probability. Models of this type are either difficult of impossible to build in terms of relational Kripkean semantics [40].We conclude by introducing general first order neighborhood frames with constant domains and we offer a general completeness result for the entire family of classical first order modal systems in terms of them, circumventing some well-known problems of propositional and first order neighborhood semantics (mainly the fact that many classical modal logics are incomplete with respect to an unmodified version of either neighborhood or relational frames). We argue that the semantical program that thus arises offers the first complete semantic unification of the family of classical first order modal logics. (shrink)

Ralph Waldo Emerson is one of the most significant figures in nineteenth-century American literature and culture-indeed, this collection argues, in the history of philosophy. The Other Emerson is a thorough reassessment of the philosophical underpinnings, theoretical innovations, and ethical and political implications of the prose writings of one of America's most enduring thinkers. Considering Emerson first and foremost as a daring and original thinker, _The Other Emerson_ focuses on three Emersonian subjects-subjectivity, the political, and the nature of philosophy-and range in (...) topic from Emerson's relationships to slavery and mourning to his place in the development of Romanticism as reread by contemporary systems theory. It is Emerson's appreciation of truth's instability that link him to the European philosophical tradition. Contributors: Eduardo Cadava, Princeton U; Sharon Cameron, Johns Hopkins U; Russell B. Goodman, U of New Mexico; Paul Grimstad, Yale U; Eric Keenaghan, U at Albany, SUNY; Gregg Lambert, Syracuse U; Sandra Laugier, Université de Picardie Jules Verne; Donald Pease, Dartmouth College. (shrink)

In this essay, Scott Pratt develops the tension at work in Democracy and Education between conceptions of multiculturalism that emerge from Dewey's commitment to progress as a process of civilization and from his contrasting commitment to a vision of progress as a localized process that requires respect for boundaries and limits. The first is related to what Patrick Wolfe has called “settler colonialism.” The second conception of multiculturalism, framed by the aims of education and the conception of growth, avoids (...) the problems of the first and provides a foundation for a practical, decolonial multiculturalism in the context of twenty-first-century education. (shrink)

Introduction -- Media and representation. On the one medium / Eric Gans -- The scapegoat mechanism and the media: beyond the folk devil paradigm / John O'Carroll -- The apocalypse will not be televised / Chris Fleming -- Film. Mirrors of nature: artificial agents in real life and virtual worlds / Paul Dumouchel -- Superheroes, scapegoats, and saviors: the problem of evil and the need for redemption / Joel Hodge -- Sanctified victimage on page and screen: The hunger games (...) as prophetic media / Debra E. Macdonald -- The mimetic e-motion: from The matrix to Avatar / Nidesh Lawtoo -- Apocalypse of the therapeutic: The cabin in the woods and the death of mimetic desire / Peter Y. Paik -- Eyes wide shut: mimesis and historical memory in Stanley Kubrick's The shining / David Humbert -- Against romantic love: mimeticism and satire in Woody Allen's Vicky, Cristina, Barcelona; you will meet a tall dark stranger; and To Rome with love / Scott Cowdell -- A beautiful crisis: Ang Lee's film adaptation of The ice storm / Carly Osborn -- Cowboy metaphysics, the virtuous-enough cowboy, and mimetic desire in Stephen Fears' The hi-lo country / Thomas Ryba -- Television. The self in crisis: watching Mad men and Homeland with Girard and Hegel / Paolo Diego Bubbio -- Media, murder, and memoir: Girardian baroque in Robert Drewe's The shark net / Rosamund Dalziell -- Conversion in Dexter / Matthew John Paul Tan and Joel Hodge. (shrink)

Questions about the role of luck in attributions of moral responsibility have troubled theorists for some time. In this paper I will explicate a position that acknowledges luck as a contributing factor to most, if not all, outcomes and consequences while denying luck the exculpatory role that some theorists contend it plays. I begin by going through the characterization of two perspectives on luck offered by Susan Wolf. From there I outline two necessary conditions for the legitimate attribution of (...) praise or blame. The first condition is that of Control. The second condition is the agent's creation of "undue risk". I revisit Wolfs two perspectives and break down the relationship between the necessary conditions and each perspective. I contend that a legitimate theory of moral responsibility must allow for factors outside of an agent's control when attempting to attribute praise or blame. Luck can be seen as one of these factors and it should not be seen as playing an exculpatory role. (shrink)

Two meanings of "subjective consequentialism" are distinguished: conscious deliberation with the aim of producing maximally-good consequences, versus acting in ways that, given one's evidence set and reasoning capabilities, is subjectively most likely to maximize expected consequences. The latter is opposed to "objective consequentialism," which demands that we act in ways that actually produce the best total consequences. Peter Railton's arguments for a version of objective consequentialism confuse the two subjective forms, and are only effective against the first. After reviewing the (...) arguments of Eric Wiland and Frances Howard-Snyder against objective consequentialism, two of Railton's arguments which might seem to count against the second form of subjective consequentialism are shown to be ineffective. This leaves subjective consequentialism as a viable theory to replace objective consequentialism with. (shrink)

In 1989, Susan Wolf convincingly warned of a troublesome consequence that should discourage any movement in American society towards physician-assisted death—a legal backlash against the gains made for limiting life-sustaining treatment. The authors demonstrate that this dire consequence did not come to pass. As physician-assisted suicide gains a foothold in USA and elsewhere, many other slippery slope arguments are being put forward. Although many of these speculations should be taken seriously, they do not justify halting the new practice. Instead, (...) our courts, regulatory agencies, journalists, professional organisations and researchers should carefully monitor and study it as it unfolds, allowing continuous improvement just as our society has done in implementing the practice of limiting life-sustaining treatment. (shrink)

The paper focuses on extending to the first order case the semantical program for modalities first introduced by Dana Scott and Richard Montague. We focus on the study of neighborhood frames with constant domains and we offer a series of new completeness results for salient classical systems of first order modal logic. Among other results we show that it is possible to prove strong completeness results for normal systems without the Barcan Formula in terms of neighborhood frames with constant (...) domains. The first order models we present permit the study of many epistemic modalities recently proposed in computer science as well as the development of adequate models for monadic operators of high probability. Models of this type are either difficult of impossible to build in terms of relational Kripkean semantics. We conclude by introducing general first order neighborhood frames and we offer a general completeness result in terms of them which circumvents some well-known problems of propositional and first order neighborhood semantics. We argue that the semantical program that thus arises surpasses both in expressivity and adequacy the standard Kripkean approach, even when it comes to the study of first order normal systems. (shrink)

Arguably, the proposition that Mark Twain is Samuel Clemens and the proposition that water is H2O are both a posteriori. Nevertheless, they both seem to be necessary. Ever since Davies and Humberstone :1–31, 1980), it has been known that two-dimensional semantics can account for this fact. But two-dimensionalism isn’t the only theory on the market that purports to do so. In this paper, I will look at two alternatives, one by Scott Soames and one by Kathrin Glüer-Pagin and Peter (...) Pagin, and argue that both of them fail. Regarding the former, I argue that the conceptually possible but metaphysically impossible worlds one is required to postulate are hard to conceive of on closer inspection. As for the latter, the proposal doesn’t work for certain modal sentences, and I show that it cannot be easily amended. (shrink)

This article contends that there are two formulations of skepticism; one centered upon epistemic investigation, the other centered upon developing the human capacity for judgment, a type of “quasi-religious” quest. The identification of these two easily confused formulations is suggested by an analysis of language usage within skeptical argumentation, supported by briefly analyzing Eric Havelock’s Preface to Plato, and confirmed by an analysis of Descartes. The significance of this confusion, i.e., the lack of progress in finding a solution to (...) the skeptical problem, is demonstrated through a critique of an article written by Barry Stroud. (shrink)

In recent years, a convergence has occurred between the disciples of Leo Strauss and those of Eric Voegelin. Spurred in part by the publication of the Strauss-Voegelin correspondence, and in part by a shared sense of persecution at the hands of the "politically correct," this convergence has taken place almost exclusively on Straussian terms. While few, if any, Straussians speak of "compactness," "differentiation," or "the ground of being," more and more Voegelinians are using Straussian catchwords and phrases like "the (...) conflict between Jerusalem and Athens," "historicism," and "natural right.". (shrink)

TOC -/- 0. Introduction (SN/CW) -/- I. Revisiting vitalist themes in 19th-century science -/- 1. Guido Giglioni (Warburg Institute) – Jean-Baptiste Lamarck and the Place of Irritability 2. in the History of Life and Death 3. Joan Steigerwald (York) – Rethinking Organic Vitality in Germany at the Turn of the Nineteenth Century 4. Juan Rigoli (Geneva) –The “Novel of Medicine” 5. Sean Dyde (Cambridge) – Life and the Mind in Nineteenth-Century Britain. Somaticism in the Wake of Phrenology. -/- II. Twentieth (...) century debates on vitalism in science and philosophy -/- 6. Brian Garrett (McMaster) – Vitalism versus Emergent Materialism 7. Christophe Malaterre (Paris) – Life as an Emergent Phenomenon: from an Alternative to Vitalism to an Alternative to Reductionism 8. Sebastian Normandin (Montreal) – Wilhelm Reich: Vitalism and Its Discontents 9. Chiara Elettra Ferrario (Wellington) and Luigi Corsi (Pisa) – Kurt Goldstein: Vitalism and the Organismic Approach 10. Giuseppe Bianco (Paris/Warwick) – The Origins of Canguilhem’s “Vitalism”. Against the Anthropology of Irritation -/- III. Vitalism and contemporary biological developments -/- 11. William Bechtel (UCSD) — Dynamic Mechanistic Explanation: Addressing the Vitalists’ Objections to Mechanistic Science 12. John Dupré and Maureen O’Malley (Exeter) – Varieties of living things: Life at the intersection of lineage and metabolism 13. J. Scott Turner (Syracuse) – Homeostasis and the forgotten vitalist roots of adaptation -/- . (shrink)

The paper focuses on extending to the first order case the semantical program for modalities first introduced by Dana Scott and Richard Montague. We focus on the study of neighborhood frames with constant domains and we offer in the first part of the paper a series of new completeness results for salient classical systems of first order modal logic. Among other results we show that it is possible to prove strong completeness results for normal systems without the Barcan Formula (...) (like FOL + K)in terms of neighborhood frames with constant domains. The first order models we present permit the study of many epistemic modalities recently proposed in computer science as well as the development of adequate models for monadic operators of high probability. Models of this type are either difficult of impossible to build in terms of relational Kripkean semantics [40].We conclude by introducing general first order neighborhood frames with constant domains and we offer a general completeness result for the entire family of classical first order modal systems in terms of them, circumventing some well-known problems of propositional and first order neighborhood semantics (mainly the fact that many classical modal logics are incomplete with respect to an unmodified version of either neighborhood or relational frames). We argue that the semantical program that thus arises offers the first complete semantic unification of the family of classical first order modal logics. (shrink)

In the mid-19 th century, increases in global migration and mobility produced a discernable rise in the number of ambiguous absences. This shift, combined with a novel expectation, linked to improved communications technology, that such absences might be resolved engendered the emergence of missing persons as a social category. A demand on the part of families of the missing that the state aid in their location would produce a Bourdieusian classification struggle over how to define and categorize this new mass (...) of absences. At issue would be whether an ambiguously absent individual was merely absent, as a routine component of social life, or whether the individual merited legitimation by the state as a new form of deviant: a "missing" person. Scholars have described the emerging administrative state’s enhanced powers of surveillance and classification and its persistent inclination to render their populations, in James Scott’s phrase, “legible.” Brought to the attention of the state, missing persons represented a body of people who had conspicuously fallen out of official sight. Yet, instead of attempting to fix this omission by gathering additional information on the lost — to, in effect, see the missing — as theories of the state would lead us to expect, the state chose to look away. In the United States, the state, in the form of municipal police departments, resisted classifying absences as cases of missingness and pushed back against families’ requests for aid. Leveraging the inherently ambiguous characteristics of the missing, the state promoted a definition of missing persons that conveniently freed it from the burden of managing an unmanageable population. In this article, drawing from archival data, I challenge prevailing theories of the modern state that emphasize its avidly classificatory nature by offering a case in which legibility was strategically withheld and a population was, in service of state interests, intentionally obscured. Only after the state lost its symbolic monopoly and the category was raced and gendered, becoming, in public discourse, associated with a socially valuable demographic – namely, young, white women – would the state, facing a threat to its legitimacy, deem the missing as worthy of being seen. (shrink)